What is the purpose of the Spark-PA study?

Spark-PA is a clinical research study exploring an investigational study drug that may help people with primary aldosteronism (PA) lower their blood pressure.

The drug is investigational. This means it can only be used for research. It is not currently approved as a treatment for high blood pressure caused by PA. 

What will happen during the study?

If you decide to join the study, participation will last up to 13 weeks and includes the following:


  • The Qualification process involves at least 4 study clinic visits and lasts up to 7 weeks. You will receive health assessments and may need to adjust your blood pressure medications.

Study Drug

  • If you qualify, you will take the study drug or placebo daily and visit the study clinic weekly for 4 weeks.
  • During this time, you will measure your blood pressure daily at home and record your measurements in a diary.

Follow up

  • About a week after your last study clinic visit, the study staff will follow up with you over the phone. They will discuss any medications you are taking and how you are feeling.

For more information on the Spark-PA study, visit

Interested in joining the Spark-PA study?

Take a brief survey to find out if you meet some of the study requirements!